The Cardiac Biomechanics Laboratory in the Department of Mechanical and Materials Engineering at the University of Denver is focused on applied and translational research in cardiovascular diseases. The lab research goal is to understand the role of biomechanics in the development and remodeling of the cardiovascular system. We use computational and experimental approaches to obtain greater insight into the complex pathways of cardiovascular diseases, and thereby to develop new diagnostic and therapeutic devices.

Below please find a brief summary of our research projects.

  • Computational Modeling and Simulation Computational Modeling and Simulation Leaflet stress and strain distribution of tissue heart valves (Mostafa Abbasi, PhD student)
  • In-Vitro Testing and Assessment In-Vitro Testing and Assessment In-vitro characterization of heart valve hemodynamics using PIV (Mohammed Barakat, PhD student)
  • Multiscale Modeling and Analysis Multiscale Modeling and Analysis Red blood cell membrane damage due to valvular stenosis (Koohyar Vahidkhah, Postdoctoral Fellow)
  • Quantitative Soft Tissue Characterization Quantitative Soft Tissue Characterization Structural and biaxial mechanical properties of normal hearts (Shahnaz Javani, MS Student)
  • Cardiovascular Tissue Engineering Cardiovascular Tissue Engineering 3D printing of heart valves and blood vessels (Ben Stewart, MS Student)
  • Ex-Vivo Testing and Evaluation Ex-Vivo Testing and Evaluation Ex-vivo porcine crystalloid-perfused beating heart platform (Rahie Talukder and Ben Stewart, MS Students)