Image caption: Three-dimensional fluid-structure interaction computational simulation of a bioprosthetic heart valve.
The DU Cardiovascular Biomechanics Lab is focused on applied and translational research in the field of cardiovascular engineering. The scope of the research projects, directed by Dr. Ali Azadani, encompasses structural heart disease including transcatheter heart valve replacement and development of patient-specific therapeutic strategies. The team is currently well established in the field of cardiovascular biomechanics, and has expertise in computational modeling and simulation, including finite element (FE) analysis, computational fluid dynamic (CFD) simulations, and fluid-solid interaction (FSI) simulations. Furthermore, the lab is equipped with state-of-the-art equipment for in vitro testing of biomaterials and medical devices. In addition to standard equipment, the lab has a custom-built pulse duplicator system for in vitro testing of surgical and transcatheter heart valves, high-resolution particle image velocimetry (PIV) system, biaxial stretching system, 3D cardiovascular ultrasound system, 3D laser scanner, and access to a 3D high-resolution digital image correlation (DIC) system. Strong collaborations exist between his lab and other research groups in the U.S. and worldwide. Moreover, the lab has a strong record of federal, industrial grant, and foundation support.
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