Welcome to the DU Cardiovascular Biomechanics Lab

The DU Cardiovascular Biomechanics Lab specializes in applied and translational research within the field of cardiovascular engineering. Led by Dr. Ali Azadani, our research projects focus on addressing structural heart disease, including the innovative development of transcatheter heart valve replacements and patient-specific therapeutic strategies. 

   Our team is distinguished in the field of cardiovascular biomechanics, with extensive expertise in computational modeling and simulation. We excel in finite element (FE) analysis, computational fluid dynamics (CFD) simulations, and fluid-solid interaction (FSI) simulations. This allows us to create highly accurate models of cardiovascular systems, predict device performance, and optimize therapeutic interventions.Our lab is also equipped with state-of-the-art technology for in vitro testing of biomaterials and medical devices. Among our advanced equipment, we feature a custom-built pulse duplicator system designed for in vitro testing of surgical and transcatheter heart valves, a high-resolution particle image velocimetry (PIV) system for flow visualization, a biaxial stretching system for material characterization, a 3D cardiovascular ultrasound system for detailed imaging, a 3D laser scanner for precise geometrical measurements, a 3D printer capable of metal printing, and access to a high-resolution 3D digital image correlation (DIC) system for surface strain analysis. 

   Our lab maintains strong collaborations with leading research groups both in the U.S. and internationally. Additionally, we have a proven track record of securing support from federal agencies, industrial partners, and foundations. Our commitment to advancing cardiovascular health through engineering innovation drives us to continually push the boundaries of what is possible. We strive to ensure that our work translates into tangible benefits for patients worldwide.